Your Guide to Evenity for Osteoporosis

If you’ve been diagnosed with osteoporosis, especially after a fracture or a very low bone density score, your doctor may recommend Evenity—a newer, advanced treatment designed to rapidly build bone and reduce fracture risk.
In this guide, you’ll learn what Evenity is, how it works, who it’s for, how long you can take it, and what to expect during and after treatment. Plus, we’ll explain why tracking your progress with a DEXA scan is essential for long-term success.
What Is Evenity?
Evenity® (generic name: romosozumab) is an osteoporosis injection approved to:
- Treat postmenopausal women at high risk for fracture
- Build new bone quickly while also slowing bone loss
- Reduce the risk of spine and non-spine fractures
Evenity is especially helpful for women who’ve already had a fracture or have not responded to other osteoporosis medications.
How Does Evenity Work?
Evenity is a dual-action monoclonal antibody therapy.
Mechanism of action:
- Blocks sclerostin, a protein that slows bone formation
- Stimulates osteoblasts (bone-building cells) to create new bone
- Simultaneously reduces bone resorption, preserving existing bone
It’s the only FDA-approved treatment that both builds and preserves bone at the same time.
How Is Evenity Given and for How Long?
- Administered as two subcutaneous injections once a month
- Treatment duration: 12 months only
- Must be followed by another medication (like a bisphosphonate or Prolia) to maintain gains
Skipping follow-up treatment may result in rapid bone loss.
Who Should Consider Evenity?
Evenity may be right for you if:
- You’re postmenopausal with severe osteoporosis (T-score ≤ -2.5)
- You’ve experienced a recent osteoporotic fracture
- Other treatments like bisphosphonates or Prolia haven’t worked or aren’t tolerated
Not recommended for:
- Patients with a history of heart attack or stroke
- Individuals with high cardiovascular risk
⚠️ Evenity Side Effects and Warnings
Common side effects:
- Joint pain
- Headache
- Injection site reactions
Serious risks (rare):
- Increased risk of heart attack, stroke, or cardiovascular death
- Low blood calcium levels (especially in people with kidney disease)
Your doctor will evaluate your heart health and calcium levels before starting.
📊 Track Your Progress with a DEXA Scan
To ensure Evenity is working, and to guide your next treatment steps, it’s critical to get DEXA scans:
- Before treatment (establish baseline bone mineral density)
- Every 1-2 months to assess gains
- During follow-up therapy to ensure bone density is maintained
At KALOS, our DEXA Scan San Francisco service provides fast, accurate insights into:
- Bone Mineral Density (BMD)
- Fracture risk
- Treatment effectiveness
Book Your DEXA Scan in San Francisco at KALOS Today
If you’re starting or finishing Evenity for osteoporosis, the best thing you can do is monitor your results with precision. At KALOS, we help you track your treatment success, identify risks early, and make data-driven decisions about your next steps.
Schedule your scan today at KALOS—your journey to stronger, healthier bones starts now.
Ready to measure what matters?
Book your DEXA scan today and stop guessing about your health.



