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Bone Health
May 15, 2025

Fosamax for Osteoporosis: How It Works, Side Effects, and Pros & Cons You Should Know

Get the facts on Fosamax for osteoporosis—how it works, side effects, and how to monitor treatment success with a DEXA Scan in San Francisco at KALOS.

Author
5 min read
Fosamax for Osteoporosis: How It Works, Side Effects, and Pros & Cons You Should Know

If you’ve been diagnosed with osteoporosis or low bone mass, you may have heard of Fosamax—one of the most commonly prescribed medications to help prevent fractures and preserve bone density. But like any medication, it’s important to understand how Fosamax works, what the side effects may be, and whether it’s the right choice for your long-term bone health.

Here’s everything you need to know about Fosamax for osteoporosis, including its benefits, risks, and how to track your progress with a DEXA scan.

What Is Fosamax and How Does It Work?

Fosamax (generic name: alendronate) is a bisphosphonate, a drug that works by slowing down the rate at which your body breaks down bone.

How does Fosamax work?

  • It binds to bone surfaces and inhibits osteoclasts—the cells responsible for bone resorption
  • This helps maintain or increase bone mineral density (BMD) and reduces the risk of spine and hip fractures

Fosamax is typically taken as:

  • A weekly oral tablet (most common)
  • A daily dose for specific cases

It’s often one of the first-line treatments for postmenopausal women, men with osteoporosis, and people on long-term steroid therapy.

⚖️ Fosamax Pros and Cons

Pros of Fosamax

  • Proven track record: Reduces risk of spine and hip fractures
  • Cost-effective: Widely available in generic form (alendronate)
  • Easy to use: Once-weekly dosing is convenient for most patients
  • Bone density improvement: Helps maintain or increase BMD in the spine and hips

Cons of Fosamax

  • Must be taken first thing in the morning, on an empty stomach, with a full glass of water
  • You must stay upright for at least 30 minutes after taking to prevent esophageal irritation
  • Not suitable for people with GI issues or trouble swallowing pills
  • Long-term use (beyond 5 years) may carry risks of:
    • Atypical femur fractures
    • Jaw osteonecrosis (rare but serious)

⚠️ Fosamax Side Effects: What You Should Know

Common side effects of Fosamax:

  • Heartburn or acid reflux
  • Stomach pain or upset
  • Constipation or diarrhea
  • Muscle or joint pain

Serious but rare side effects:

  • Esophageal irritation or ulcers
  • Jaw osteonecrosis (usually after dental procedures or in cancer patients)
  • Atypical femoral fractures (associated with long-term use)

Fosamax side effects can often be reduced by following proper dosing instructions and using the drug for the appropriate duration.

📆 How Long Should You Take Fosamax?

  • Usually prescribed for 3–5 years, followed by a drug holiday depending on your fracture risk
  • Ongoing use beyond 5 years may be appropriate for those with very high fracture risk
  • Decisions should be based on your DEXA scan results, age, and overall health

📊 Track Your Progress with a DEXA Scan

The only way to know if Fosamax is working for you is by monitoring your bone mineral density regularly.

With a DEXA scan, you can:

  • Track BMD changes over time
  • Evaluate fracture risk
  • Decide when it’s time for a medication break or switch

At KALOS, our DEXA Scan San Francisco service helps you and your doctor make data-driven decisions about your osteoporosis treatment plan.

Book Your DEXA Scan in San Francisco at KALOS Today

If you're starting or currently taking Fosamax for osteoporosis, make sure you're tracking how well it's working with a DEXA scan at KALOS. We provide fast, accurate bone density testing to help you take control of your long-term bone health.

Schedule your scan today at KALOS—your journey to data-driven bone protection starts now.

Schedule your DEXA scan today!

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